Guest Lecture: Thierry Brigaud

Fluorine in life sciences: the surprise guest

Thierry Brigaud is Professor in Organic Chemistry and Deputy Director of the BioCIS Unit (UMR-CNRS-8076) at CY Cergy-Paris University.

Although fluorine is the 13^th most common element in the earth’s crust it is virtually absent from the biosphere. Thus, nothing destined fluorinated compounds to become major players in medicinal chemistry for the last thirty years. To explain this paradox will be presented in this seminar, a state of the art of recent developments in the rational design of fluorinated compounds for pharmaceutical use but also as a tool for imaging, diagnosis and investigation of biological processes. The specific synthetic methods for the incorporation of fluorine atoms will be briefly and synthetically presented. The new directions and perspectives offered by the recent introduction of fluorinated compounds in the field of biomedical applications of peptides will also be outlined.

Day: 30 of november 2021 from 12h30 to 14h00

The hybrid guest lecture is organized in presence at the MIR Auditorium in Neuville-sur-Oise and remotely on Zoom.

The video is posted on the CY AS YouTube channel.