Published on February 17, 2022 Updated on March 1, 2022


Aurica Farcas
Aurica Farcas
"Petru Poni" Institute of Macromolecular Chemistry, Iasi - Romania
Visiting scholar invited by research center LPPI
Curriculum Vitae

Research project

Conjugated polyrotaxanes and their applications in optoelectronics and biology

This project builds on the collaborative work with LPPI that has been ongoing for several years and also
aims at developing a collaboration recently initiated with LAMBE during the last stay as a fellow in residence in
the spring of 2019 (paper submitted to ChemComm. in september 2019). Indeed, the objective is to prepare
an European project application, with a consortium extended to LAMBE. For this purpose, new polyrotaxanes
have to be synthesized, based on conjugated monomers or polymers (guests) with native γ-cyclodextrin and
permodified β- or γ-cyclodextrin or cucurbit[n]urils macrocyclic molecules (hosts). In these supramolecular
architectures, no covalent bonds between the host and guest molecules are present and the stability of the
inclusion complex is ensured by the topological constraints (physical interactions).
During the stay in LPPI, new supramolecular structures will be synthesized following three steps: (a)
synthesis of new host and guest systems; (b) synthesis of inclusion complexes or host-guest systems; (c)
synthesis of conjugated polyrotaxanes.
Such large range of synthesized conjugated polymers should allow the development of new materials with
controlled properties and applications in the fields of optoelectronics and biology.
Therefore, in LPPI, all synthesized supramolecular polymers will be characterized in terms of their physicochemical,
optical and electronic properties. Their contribution in the field of organic electronic materials will
thus be assessed.
In LAMBE, these supramolecular compounds will be investigated for the rapid and real time probing of the
capability to form host-guest complexes with various types of guest molecules, such as amino acids for lowcost
protein sequencing applications. Besides that, such supramolecular assemblies could be used as a
molecular seizer at a single molecule level or as new classes of biomimetic ionic channels.
The whole project should provide the development of research at the interface between chemistry, physics
and biology, with promising applications in the fields of optoelectronics and biology.